USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: MTAP_HUMAN USC-OGP 2-DE database:  MTAP_HUMAN MTAP_HUMAN General information about the entry View entry in simple text format Entry name MTAP_HUMAN Primary accession number Q13126 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}; EC=2.4.2.28 {ECO:0000255|HAMAP-Rule:MF_03155}; AltName: Full=5'-methylthioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}; Short=MTA phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}; Short=MTAP {ECO:0000255|HAMAP-Rule:MF_03155}; Short=MTAPase {ECO:0000255|HAMAP-Rule:MF_03155};. Gene name Name=MTAP {ECO:0000255|HAMAP-Rule:MF_03155} Synonyms=MSAP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1270: pI=6.97; Mw=28628 Cross-references UniProtKB/Swiss-Prot Q13126; MTAP_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MTAP_HUMAN Primary accession number Q13126 Secondary accession number(s) I2G7M5 I2G7M6 I2G7M7 I2G7M8 I2G7M9 I2G7N0 Q5T3P3 Q9H010 Sequence was last modified on  April 3, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 177) Name and origin of the protein Description RecName: Full=S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}; EC=2.4.2.28 {ECO:0000255|HAMAP-Rule:MF_03155}; AltName: Full=5'-methylthioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}; Short=MTA phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}; Short=MTAP {ECO:0000255|HAMAP-Rule:MF_03155}; Short=MTAPase {ECO:0000255|HAMAP-Rule:MF_03155}; Gene name Name=MTAP {ECO:0000255|HAMAP-Rule:MF_03155} Synonyms=MSAP Encoded on Name=MTAP {ECO:0000255|HAMAP-Rule:MF_03155}; Synonyms=MSAP Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Glycosyltransferase; Nucleus; Polymorphism; Purine salvage; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U22233; AAA81646.1; -; mRNA EMBL L40432; AAG38871.1; -; mRNA EMBL L42634; AAR24607.2; -; Genomic_DNA EMBL L42627; AAR24607.2; JOINED; Genomic_DNA EMBL L42628; AAR24607.2; JOINED; Genomic_DNA EMBL L42629; AAR24607.2; JOINED; Genomic_DNA EMBL L42630; AAR24607.2; JOINED; Genomic_DNA EMBL L42631; AAR24607.2; JOINED; Genomic_DNA EMBL L42632; AAR24607.2; JOINED; Genomic_DNA EMBL L42633; AAR24607.2; JOINED; Genomic_DNA EMBL HE654772; CCF77345.1; -; mRNA EMBL HE654773; CCF77346.1; -; mRNA EMBL HE654774; CCF77347.1; -; mRNA EMBL HE654775; CCF77348.1; -; mRNA EMBL HE654776; CCF77349.1; -; mRNA EMBL HE654777; CCF77350.1; -; mRNA EMBL AY712791; AAU04442.1; -; mRNA EMBL AL359922; CAI16481.1; -; Genomic_DNA EMBL CH471071; EAW58606.1; -; Genomic_DNA EMBL BC026106; AAH26106.1; -; mRNA CCDS CCDS6509.1; -. [Q13126-1]; . PIR I38969; I38969; . RefSeq NP_002442.2; NM_002451.3. [Q13126-1]; . UniGene Hs.193268; -; . PDB 1CB0; X-ray; 1.70 A; A=1-283 PDB 1CG6; X-ray; 1.70 A; A=1-283 PDB 1K27; X-ray; 1.95 A; A=1-283 PDB 1SD1; X-ray; 2.03 A; A=1-283 PDB 1SD2; X-ray; 2.10 A; A=1-283 PDB 3LN5; X-ray; 1.90 A; C=227-237 PDB 3OZC; X-ray; 1.93 A; A=1-283 PDB 3OZD; X-ray; 2.10 A; A/B=1-283 PDB 3OZE; X-ray; 2.00 A; A/B/C/D/E/F=1-283 PDB 5EUB; X-ray; 1.81 A; A=1-283 PDBsum 1CB0; -; . PDBsum 1CG6; -; . PDBsum 1K27; -; . PDBsum 1SD1; -; . PDBsum 1SD2; -; . PDBsum 3LN5; -; . PDBsum 3OZC; -; . PDBsum 3OZD; -; . PDBsum 3OZE; -; . PDBsum 5EUB; -; . ProteinModelPortal Q13126; -; . SMR Q13126; -; . BioGrid 110611; 48; . IntAct Q13126; 12; . MINT MINT-268764; -; . STRING 9606.ENSP00000369519; -; . BindingDB Q13126; -; . ChEMBL CHEMBL4941; -; . DrugBank DB02933; 5'-Deoxy-5'-(Methylthio)-Tubercidin; . DrugBank DB02282; 5'-Deoxy-5'-Methylthioadenosine; . DrugBank DB00173; Adenine; . DrugBank DB02281; Formycin; . iPTMnet Q13126; -; . PhosphoSitePlus Q13126; -; . BioMuta MTAP; -; . DMDM 143811423; -; . REPRODUCTION-2DPAGE Q13126; -; . UCD-2DPAGE Q13126; -; . EPD Q13126; -; . MaxQB Q13126; -; . PaxDb Q13126; -; . PeptideAtlas Q13126; -; . PRIDE Q13126; -; . DNASU 4507; -; . Ensembl ENST00000380172; ENSP00000369519; ENSG00000099810. [Q13126-1]; . Ensembl ENST00000580900; ENSP00000463424; ENSG00000099810. [Q13126-3]; . GeneID 4507; -; . KEGG hsa:4507; -; . UCSC uc003zph.4; human. [Q13126-1]; . CTD 4507; -; . DisGeNET 4507; -; . GeneCards MTAP; -; . H-InvDB HIX0007954; -; . H-InvDB HIX0025895; -; . HGNC HGNC:7413; MTAP; . HPA HPA046915; -; . MalaCards MTAP; -; . MIM 112250; phenotype; . MIM 156540; gene; . neXtProt NX_Q13126; -; . OpenTargets ENSG00000099810; -; . Orphanet 85182; Diaphyseal medullary stenosis - bone malignancy; . PharmGKB PA31220; -; . eggNOG KOG3985; Eukaryota; . eggNOG COG0005; LUCA; . GeneTree ENSGT00550000074874; -; . HOGENOM HOG000228986; -; . HOVERGEN HBG002487; -; . KO K00772; -; . OrthoDB EOG091G0CQI; -; . PhylomeDB Q13126; -; . TreeFam TF312883; -; . BioCyc MetaCyc:HS01913-MONOMER; -; . BRENDA 2.4.2.28; 2681; . Reactome R-HSA-1237112; Methionine salvage pathway; . SABIO-RK Q13126; -; . SignaLink Q13126; -; . UniPathway UPA00904; UER00873; . ChiTaRS MTAP; human; . EvolutionaryTrace Q13126; -; . GeneWiki MTAP; -; . GenomeRNAi 4507; -; . PRO PR:Q13126; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000099810; -; . CleanEx HS_MTAP; -; . ExpressionAtlas Q13126; baseline and differential; . Genevisible Q13126; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IEA:UniProtKB-SubCell; . GO GO:0004645; F:phosphorylase activity; TAS:ProtInc; . GO GO:0017061; F:S-methyl-5-thioadenosine phosphorylase activity; TAS:Reactome; . GO GO:0019509; P:L-methionine salvage from methylthioadenosine; TAS:Reactome; . GO GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc; . GO GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW; . Gene3D 3.40.50.1580; -; 1; . HAMAP MF_01963; MTAP; 1; . InterPro IPR010044; MTAP; . InterPro IPR000845; Nucleoside_phosphorylase_d; . InterPro IPR018099; Purine_phosphorylase-2_CS; . PANTHER PTHR42679; PTHR42679; 1; . Pfam PF01048; PNP_UDP_1; 1; . SUPFAM SSF53167; SSF53167; 1; . TIGRFAMs TIGR01694; MTAP; 1; . PROSITE PS01240; PNP_MTAP_2; 1; .

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